| 8th September 2021, 20.45 CET | |||
 MACEDONIA 0:0 ROMANIA  |
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| HT 0:0 | |||
| Goals: / | |||
| Stadium: National Arena Toshe Proeski in Skopje |
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| Attendance: 5,260 | |||
| MKD | ROU | ||
| 1. | Stole Dimitrievski (GK) | 1. | Florin Niță (GK) |
| 6. | Visar Musliu  86′ |
2. | Andrei Rațiu |
| 7. | Elif Elmas | 5. | Ionuț Nedelcearu |
| 8. | Ezgjan Alioski | 6. | Vlad Chiricheș (C) |
| 10. | Enis Bardhi  90′ |
8. | Alexandru Cicâldău |
| 11. | Darko Churlinov 78′ |
9. | Jovan Marković 63′ |
| 13. | Stefan Ristovski (C) | 13. | Deian Sorescu 74′ |
| 14. | Darko Velkovski 64′ |
14. | Dragoș Nedelcu 48′ 63′ |
| 19. | Milan Ristovski 27′ 64′ |
20. | Dennis Man |
| 20. | Stefan Spirovski 78′ |
22. | Mário “Camora” Jorge Malico Paulino |
| 21. | Tihomir Kostadinov 71′ |
23. | Nicolae Stanciu |
| Substitutes: | |||
| 2. | Todor Todoroski | 3. | Alin Toșca |
| 3. | Stefan Ashkovski  90′ |
4. | Cristian Manea |
| 4. | Kire Ristevski 64′ |
7. | Andrei Cordea 63′ |
| 5. | Nikola Serafimov | 11. | Marius Marin 74′ |
| 9. | Aleksandar Trajkovski 78′ |
12. | Andrei Daniel Vlad (GK) |
| 12. | Dejan Iliev (GK) | 17. | Adrian Rus |
| 15. | Jani Atanasov | 18. | Răzvan Marin 63′ |
| 16. | Boban Nikolov 78′ |
19. | Darius Olaru |
| 17. | Daniel Avramovski | 21. | Virgil Ghiță |
| 18. | Adis Jahovikj 64′ |
/ | |
| 22. | Damjan Shishkovski (GK) | / | |
| 23. | Bojan Miovski | / | |
| Coaches: | |||
| Blagoja Milevski |
Mirel Rădoi |
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| Officials: | |||
Referee: Antonio Miguel Mateu Lahoz  |
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| Assistants: Pau Norbert Cebrián Devís, Roberto Díaz Pérez Del Palomar |
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Fourth official: Serdar Gözübüyük  |
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| VAR: Juan Martínez Munuera |
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| Assistant VAR: Diego Barbero Sevilla |
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NOTE: Limited number of spectators due to the COVID-19 pandemic.
The anthems:
Highlights:
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