Round of 32

23.09.2020 at 15.30 CET:
Kit-Go (2) – Skopje (2)
Pobeda (2) – Makedonija GjP (1)
Ljuboten (3) – Pelsiter (1)
Sloga 1934 (2) – Shkupi (1)
Vardari (2) – Vardar (1)
Veleshta (2) – Kozhuf (2)
Rosoman 83 (2) – Belasica (1)
Ohrid (2) – Renova (1)
Teteks (2) – Sileks (1)
Sasa (2) – Borec (1)
Gostivar (2) – Tikvesh (2)
Vlazrimi 77 (2) – Rabotnichki (1)

Akademija Pandev (1), Bregalnica (2), Shkendija (1) and Struga (1) had a bye as semifinalists of the interrupted last season.

Round of 16

21.10.2020

Akademija Pandev (1)
Bregalnica (2)
Shkendija (1)
Struga (1)

Quarter-finals

25.11.2020

Semifinals

07.04.2021

Final

19.05.2021