Second wins for Plachkovica and Belasica, second defeats for Rabotnik Djumajlija and newcomers 14 Oktomvri 1946.
Napredok Radovo – Bregalnica Golak 1:0
Rabotnik Djumajlija – Tiverija 0:1
Osogovo – Babi 3:1
Plachkovica – Ovche Pole 3:1
Sloga 1934 – 14 Oktomvri 1946 2:0
Belasica – Sasa 5:1
| MP | W | D | L | +/- | P | |||
| Plachkovica | 2 | 2 | 0 | 0 | 10:1 | 6 | play-off | |
| Belasica | 2 | 2 | 0 | 0 | 6:1 | 6 | ||
| Osogovo | 2 | 1 | 1 | 0 | 5:3 | 4 | ||
| Babi | 2 | 1 | 0 | 1 | 4:4 | 3 | ||
| Sloga 1934 | 2 | 1 | 0 | 1 | 4:4 | 3 | ||
| Bregalnica Golak | 2 | 1 | 0 | 1 | 2:2 | 3 | ||
| Tiverija | 2 | 1 | 0 | 1 | 2:2 | 3 | ||
| Napredok Radovo | 2 | 1 | 0 | 1 | 1:1 | 3 | ||
| Sasa | 2 | 1 | 0 | 1 | 5:7 | 3 | ||
| Ovche Pole | 2 | 0 | 1 | 1 | 3:5 | 1 | ||
| Rabotnik Djumajlija | 2 | 0 | 0 | 2 | 1:4 | 0 | relegation | |
| 14 Oktomvri 1946 | 2 | 0 | 0 | 2 | 0:9 | 0 | relegation | |
Round 2 is scheduled for 7 September at 16.30 CET:
Sasa vs. Napredok Radovo
14 Oktomvri 1946 vs. Belasica
Ovche Pole vs. Sloga 1934
Babi vs. Plachkovica
Tiverija vs. Osogovo
Bregalnica Golak vs. Rabotnik Djumajlija