Vardar Negotino gave a lesson to third placed Prevalec, while Mladost Udovo recorded an important road win in Bashino village thanks to a direct freek kick goal.
Vardar Negotino – Partizan 4:0
Ilinden 1955 – Mladost Udovo 0:1
Sirkovo – Varosh 0:2
Prevalec – Golemo Konjari 2:1
Mladost Krivogashtani – Kozhuf 5:3
Babuna, Mlekar and Rosoman 83 are free.
| Pl. | W | D | L | +/- | P | |||
| Vardar Negotino | 20 | 13 | 3 | 4 | 53:19 | 42 | play-off | |
| Babuna | 20 | 12 | 3 | 5 | 36:20 | 39 | ||
| Partizan | 21 | 10 | 5 | 6 | 39:23 | 38 | ||
| Varosh | 20 | 11 | 3 | 6 | 33:18 | 36 | ||
| Mlekar | 20 | 9 | 7 | 4 | 29:18 | 34 | ||
| Mladost Udovo | 21 | 8 | 9 | 4 | 35:20 | 33 | ||
| Golemo Konjari | 20 | 9 | 5 | 6 | 27:19 | 32 | (relegation) | |
| Prevalec | 21 | 7 | 4 | 10 | 22:36 | 25 | (relegation) | |
| Mladost Krivogashtani | 21 | 7 | 3 | 11 | 33:59 | 24 | (relegation) | * |
| Ilinden 1955 | 19 | 7 | 1 | 11 | 24:32 | 22 | (relegation) | * |
| Kadino | 13 | 6 | 1 | 6 | 27:34 | 19 | relegated | |
| Rosoman 83 | 19 | 6 | 2 | 11 | 28:41 | 17 | relegation | -3 |
| Sirkovo | 21 | 3 | 3 | 16 | 18:47 | 12 | relegation | |
| Kozhuf | 20 | 3 | 3 | 14 | 25:46 | 9 | relegation | -3 |
^ From next season all 3rd Leagues will feature 12 teams, so this season will see more teams get relegated. Also, the correct number of relegated teams will be known after the conclusion of the Second League as it depends how many teams from there will be relegated into each third league. Currently in the Second League, there are 4 teams that in case of relegation will join the South (11 Oktomvri, Borec, Miravci and Pobeda Junior).
* Kadino is disqualified for not appearing in two games and all of their second half-season results got erased.
* 11 Oktomvri and Borec got relegated from the Second League.
Round 25 is scheduled for 30 April at 17.00 CET:
Kozhuf vs. Prevalec
Golemo Konjari vs. Sirkovo
Babuna vs. Ilinden 1955
Mladost Udovo vs. Rosoman 83
Partizan vs. Mlekar
Mladost Krivogashtani, Vardar Negotino and Varosh are free.