| 29th March 2022, 20.45 CET | |||
 PORTUGAL 2:0 MACEDONIA  |
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| HT 1:0 | |||
| Goals: 32′, 65′ Bruno Fernandes | |||
| Stadium: Dragão in Porto |
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| Attendance: | |||
| POR | MKD | ||
| 2. | Nuno Alexandre Tavares Mendes | 1. | Stole Dimitrievski (GK) |
| 3. | Kepler Laveran de Lima Ferreira “Pepe” | 5. | Arijan Ademi |
| 7. | Cristiano Ronaldo dos Santos Aveiro (C) | 6. | Visar Musliu  68′ |
| 8. | João Filipe Iria Santos Moutinho  90’+1 |
7. | Elif Elmas 87′ |
| 10. | Bernardo Mota Veiga de Carvalho e Silva 87′ |
8. | Ezgjan Alioski 74′ |
| 11. | Bruno Miguel Borges Fernandes 87′ |
9. | Aleksandar Trajkovski 59′ |
| 13. | Danilo Luís Hélio Pereira | 10. | Enis Bardhi |
| 16. | Otávio Edmilson da Silva Monteiro 76′ |
13. | Stefan Ristovski (C) |
| 19. | Diogo “Jota” José Teixeira da Silva 76′ |
14. | Darko Velkovski |
| 20. | João Pedro Cavaco Cancelo 68′ |
19. | Milan Ristovski 46′ |
| 22. | Diogo Meireles da Costa (GK) | 21. | Tihomir Kostadinov 75′ |
| Substitutes: | |||
| 1. | Rui Pedro dos Santos Patrício (GK) | 2. | Todor Todoroski |
| 4. | Vítor Machado Ferreira “Vitinha”  90’+1 |
3. | Stefan Ashkovski 75′ |
| 5. | Raphaël Adelino José Guerreiro 76′ |
4. | Kire Ristevski |
| 6. | José Miguel da Rocha Fonte | 11. | Darko Churlinov 59′ |
| 9. | André Miguel Valente da Silva | 12. | Kristijan Naumovski (GK) |
| 12. | José Pedro Malheiro de Sá (GK) | 15. | Nikola Serafimov |
| 14. | William Silva de Carvalho 76′ |
16. | Boban Nikolov 87′ |
| 15. | Rafael Alexandre da Conceição Leão | 17. | David Babunski |
| 17. | Gonçalo Manuel Ganchinho Guedes | 18. | Dorian Babunski |
| 18. | Matheus Luiz Nunes 87′ |
20. | Stefan Spirovski |
| 21. | Cédric Ricardo Alves Soares | 22. | Damjan Shishkovski (GK) |
| 23. | João Félix Sequeira 87′ |
23. | Bojan Miovski 46′ |
| Coaches: | |||
| Fernando Manuel Fernandes da Costa Santos |
Blagoja Milevski |
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| Officials: | |||
Referee: Anthony Taylor  |
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| Assistants: Gary Beswick, Adam Nunn |
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| Fourth official: Michael Oliver |
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| VAR: Chris Kavanagh |
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| VAR assistant: Stuart Attwell |
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The goals:
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