Golemo Konjari destroyed Kadino with 7:0 in a match that didn’t last for 90 minutes as the visitors were left with only 6 players.
Golemo Konjari – Kadino 7:0
Varosh – Kozhuf 2:1
Babuna – Mladost Krivogashtani postponed for Wednesday at 16.00 CET
Mladost Udovo – Prevalec 2:2
Mlekar – Ilinden 1955 0:0
Vardar Negotino – Rosoman 83 4:2
Partizan and Sirkovo are free.
| Pl. | W | D | L | +/- | P | |||
| Vardar Negotino | 18 | 12 | 3 | 3 | 49:18 | 39 | play-off | |
| Babuna | 18 | 11 | 3 | 4 | 33:19 | 36 | ||
| Varosh | 18 | 10 | 3 | 5 | 28:17 | 33 | ||
| Partizan | 18 | 8 | 5 | 5 | 35:19 | 32 | ||
| Mladost Udovo | 19 | 7 | 9 | 3 | 33:18 | 30 | ||
| Mlekar | 18 | 8 | 6 | 4 | 28:18 | 30 | ||
| Golemo Konjari | 18 | 8 | 5 | 5 | 29:15 | 29 | (relegation) | |
| Ilinden 1955 | 18 | 8 | 1 | 9 | 26:31 | 25 | (relegation) | |
| Rosoman 83 | 18 | 7 | 1 | 10 | 32:40 | 19 | (relegation) | -3 |
| Prevalec | 18 | 5 | 4 | 9 | 18:30 | 19 | (relegation) | |
| Kadino | 18 | 6 | 1 | 11 | 33:53 | 19 | relegation | |
| Mladost Krivogashtani | 17 | 5 | 3 | 9 | 26:52 | 18 | relegation | |
| Kozhuf | 18 | 3 | 3 | 12 | 20:38 | 9 | relegation | -3 |
| Sirkovo | 18 | 2 | 3 | 14 | 16:40 | 9 | relegation | |
* From next season all 3rd Leagues will feature 12 teams, so this season will see more teams get relegated. Also, the correct number of relegated teams will be known after the conclusion of the Second League as it depends how many teams from there will be relegated into each third league. Currently in the Second League, there are 4 teams that in case of relegation will join the South (11 Oktomvri, Borec, Miravci and Pobeda Junior).
Round 22 is scheduled for 12 April at 16.00 CET:
Kadino vs. Vardar Negotino
Rosoman 83 vs. Mlekar
Ilinden 1955 vs. Partizan
Sirkovo vs. Mladost Udovo
Prevalec vs. Babuna
Mladost Krivogashtani vs. Varosh
Kozhuf vs. Golemo Konjari