First win for Rabotnik Djumajlija as they surprised Osogovo, Belasica held by Babi, while Ovche Pole destroyed Sasa.
14 Oktomvri 1946 – Napredok Radovo 1:5
Ovche Pole – Sasa 7:1
Babi – Belasica 1:1
Tiverija – Sloga 1934 2:1
Bregalnica Golak – Plachkovica 1:1
Rabotnik Djumajlija – Osogovo 2:1
| MP | W | D | L | +/- | P | |||
| Plachkovica | 5 | 3 | 2 | 0 | 13:2 | 11 | play-off | |
| Belasica | 4 | 3 | 1 | 0 | 15:3 | 10 | ||
| Napredok Radovo | 5 | 3 | 1 | 1 | 10:4 | 10 | ||
| Ovche Pole | 4 | 2 | 1 | 1 | 14:6 | 7 | ||
| Osogovo | 4 | 2 | 1 | 1 | 8:5 | 7 | ||
| Babi | 5 | 2 | 1 | 2 | 8:7 | 7 | ||
| Bregalnica Golak | 4 | 2 | 1 | 1 | 5:4 | 7 | ||
| Tiverija | 5 | 2 | 1 | 2 | 4:5 | 7 | ||
| Sasa | 5 | 2 | 1 | 2 | 11:18 | 7 | ||
| Rabotnik Djumajlija | 5 | 1 | 0 | 4 | 4:9 | 3 | ||
| Sloga 1934 | 5 | 1 | 0 | 4 | 5:13 | 3 | relegation | |
| 14 Oktomvri 1946 | 5 | 0 | 0 | 5 | 4:25 | 0 | relegation | |
Postponed games of Round 4 are scheduled for 24 September at 15.30 CET:
Osogovo vs. Bregalnica Golak
Belasica vs. Ovche Pole
Round 6 is scheduled for 28 September at 15.30 CET:
Napredok Radovo vs. Osogovo
Plachkovica vs. Rabotnik Djumajlija
Sloga 1934 vs. Bregalnica Golak
Belasica vs. Tiverija
Sasa vs. Babi
14 Oktomvri 1946 vs. Ovche Pole